Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17710969 | 0.79 | KDM4E (0.57) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 | |
| SCHEMBL17710972 | 0.79 | KDM4E (0.57) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 | |
| SCHEMBL11498981 | 0.74 | RELA (0.48) | IDO1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9266383 | 0.73 | KDM4E (0.41) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 | |
| SCHEMBL21356554 | 0.73 | CYP1A1 (0.57) | KDM4ECYP3A4CYP1A2NPC1RAB9A | |
| SCHEMBL9266380 | 0.73 | KDM4E (0.41) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 | |
| SCHEMBL4763549 | 0.72 | CA1 (0.39) | ALDH1A1 | |
| SCHEMBL23728056 | 0.71 | MAPT (0.60) | KDM4ECYP3A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23728057 | 0.71 | MAPT (0.60) | KDM4ECYP3A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8709348 | 0.71 | CYP3A4 (0.37) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391191-B1 | (METH)ACRYLIC POLYMERS GRAFTED WITH POLYCARBONATE CHAINS, THEIR MANUFACTURE AND USE | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |
| EP-0292785-B1 | VINYL COPOLYMERES CONTAINING GRAFTED POLYCARBONATE CHAINS, THEIR MANUFACTURE AND USE | BAYER AG (DE) | 1991-06-05 | — | — | EP | disclosed |