Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.57 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | NQO2 | P16083 | 4/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | AHR | P35869 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.57 |
| ▸ | TUBB | P07437 | 2/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356550 | 0.82 | ESR1 (0.50) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL3716476 | 0.82 | CYP1A1 (0.50) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL3716473 | 0.82 | CYP1A1 (0.50) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL21370549 | 0.79 | CYP1A1 (0.52) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL21370548 | 0.79 | CYP1A1 (0.52) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL28735682 | 0.79 | CYP3A4 (0.59) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL9266383 | 0.76 | KDM4E (0.41) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL9266380 | 0.76 | KDM4E (0.41) | CYP1A1CYP1B1ESR1NQO2TTR | |
| SCHEMBL9517612 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL4763549 | 0.75 | CA1 (0.39) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365208-B2 | Silylated derivatives of resveratrol and the use thereof in neurodegenerative, neurological or inflammatory diseases | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2022-06-21 | — | — | US | claimed |
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2019-09-19 | — | — | US | claimed |
| US-11365208-B2 | Silylated derivatives of resveratrol and the use thereof in neurodegenerative, neurological or inflammatory diseases | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2022-06-21 | — | — | US | disclosed |
| EP-3549929-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2019-10-09 | — | — | EP | disclosed |
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365208-B2 | Silylated derivatives of resveratrol and the use thereof in neurodegenerative, neurological or inflammatory diseases | SNCA, SIRT1, SIRT5 | CYP1A1 2689/4885CYP1B1 3037/4885ESR1 2092/4885 |
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | SIRT1, SIRT3, SIRT2 | CYP1A1 2022/4885CYP1B1 2129/4885ESR1 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.