Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29012727 | 1.00 | TSHR (0.38) | TSHRTDP1MGAMCYP2C9 | |
| SCHEMBL20876354 | 1.00 | TSHR (0.38) | TSHRTDP1MGAMCYP2C9 | |
| SCHEMBL10409177 | 1.00 | TSHR (0.38) | TSHRTDP1MGAMCYP2C9 | |
| SCHEMBL7417972 | 1.00 | TSHR (0.38) | TSHRTDP1MGAMCYP2C9 | |
| SCHEMBL9449043 | 0.87 | LMNA (0.31) | TSHRTDP1MGAM | |
| SCHEMBL10038815 | 0.85 | MGAM (0.30) | MGAM | |
| SCHEMBL4366157 | 0.83 | MGAM (0.32) | TSHRTDP1MGAM | |
| SCHEMBL10771079 | 0.83 | — | — | |
| SCHEMBL19049953 | 0.83 | — | — | |
| SCHEMBL15338521 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233602-B1 | CHIRAL REACTION PRODUCTS OF MESOGENIC MOLECULAR COMPONENTS AND BIFUNCTIONALLY REACTIVE BUTANE-TETRAOL DERIVATIVES AND THEIR USE AS DOPING AGENTS FOR LIQUID CRYSTAL PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |
| US-4968820-A | TWISTABLE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0233602-A2 | Chiral reaction products of mesogenic molecular components and bifunctionally reactive butane-tetraol derivatives and their use as doping agents for liquid crystal phases | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-26 | — | — | EP | disclosed |