Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20876354 | 0.87 | TSHR (0.38) | MGAMTDP1TSHR | |
| SCHEMBL29012727 | 0.87 | TSHR (0.38) | MGAMTDP1TSHR | |
| SCHEMBL9511317 | 0.87 | TSHR (0.38) | MGAMTDP1TSHR | |
| SCHEMBL10409177 | 0.87 | TSHR (0.38) | MGAMTDP1TSHR | |
| SCHEMBL7417972 | 0.87 | TSHR (0.38) | MGAMTDP1TSHR | |
| SCHEMBL10309515 | 0.84 | LMNA (0.33) | LMNATSHR | |
| SCHEMBL13672319 | 0.84 | LMNA (0.33) | LMNATSHR | |
| SCHEMBL16994582 | 0.78 | — | — | |
| SCHEMBL3744813 | 0.78 | — | — | |
| SCHEMBL13951959 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119806-A1 | ARYLNAPHTHALENE LACTONE DERIVATIVES AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2017-05-04 | — | — | US | disclosed |
| US-5243065-A | Exhibit ferroelectricity; optoelectronics, display devices | IDEMITSU KOSAN CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0362714-B1 | LIQUID-CRYSTALLINE COMPOUNDS AND LIQUID-CRYSTALLINE POLYMERS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-5190687-A | Polyepoxide or polyether polymers with ester groups that exhibit ferroelectricity with high speed response to electric fields | IDEMITSU KOSAN CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0362714-A2 | Liquid-crystalline compounds and liquid-crystalline polymers | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119806-A1 | ARYLNAPHTHALENE LACTONE DERIVATIVES AND METHODS OF MAKING AND USING THEREOF | PGLS, NAPEPLD, PLCD1 | LMNA 1671/4885MGAM 1572/4885CNR1 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.