SCHEMBL9511341

SCHEMBL9511341

Clc1cc2c(c(Cl)c1Cl)Sc1c(cc(Cl)c(Cl)c1Cl)O2

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AHR P35869 15/20 0.50
FLT1 P17948 1/20 0.48
CYP3A4 P08684 2/20 0.39
HPGD P15428 2/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308926 0.80 AHR (0.42) AHRFLT1
SCHEMBL9508164 0.80 AHR (0.50) AHRFLT1CYP3A4
SCHEMBL9510018 0.77 CYP3A4 (0.34) AHRFLT1CYP3A4
SCHEMBL9511229 0.76 AHR (0.38) AHRFLT1
SCHEMBL9509978 0.76 AHR (0.38) AHRFLT1
SCHEMBL9510158 0.74 AHR (0.37) AHRFLT1
SCHEMBL9508936 0.73 AHR (0.35) AHRFLT1HSP90AA1
SCHEMBL9510067 0.73 AHR (0.35) AHRFLT1CYP3A4HPGD
SCHEMBL2464142 0.70 AHR (0.82) AHRFLT1CYP3A4HPGDTSHR
SCHEMBL29353168 0.70 AHR (0.82) AHRFLT1CYP3A4HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed