SCHEMBL9510067

SCHEMBL9510067

CC(=O)c1c(Cl)cc2c(c1Cl)Sc1c(cc(Cl)c(C(C)=O)c1Cl)O2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.35
FLT1 P17948 1/20 0.35
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511203 0.89 AHR (0.34) AHRFLT1
SCHEMBL9507662 0.82 GAA (0.36) AHRFLT1MEN1CYP3A4HPGD
SCHEMBL9508182 0.78 ALDH1A1 (0.38) MEN1HPGDKMT2A
SCHEMBL9508968 0.77 MEN1 (0.33) MEN1CYP3A4HPGDKMT2A
SCHEMBL9511341 0.73 AHR (0.50) AHRFLT1CYP3A4HPGD
SCHEMBL6308926 0.72 AHR (0.42) AHRFLT1
SCHEMBL9510033 0.70 GAA (0.37) MEN1CYP3A4HPGDKMT2A
SCHEMBL9511428 0.69 GAA (0.36) MEN1HPGDKMT2A
SCHEMBL12325017 0.69 KMT2A (0.39) AHRMEN1CYP3A4HPGDKMT2A
SCHEMBL9509978 0.68 AHR (0.38) AHRFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed