Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292263 | 1.00 | KDM4E (0.33) | KDM4EHPGDALDH1A1MAPTHTT | |
| SCHEMBL16169940 | 0.86 | — | — | |
| SCHEMBL3561873 | 0.83 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHTTPOLB | |
| SCHEMBL10567969 | 0.82 | TSHR (0.39) | POLB | |
| SCHEMBL28570275 | 0.79 | CCR2 (0.33) | — | |
| SCHEMBL15329859 | 0.77 | — | — | |
| SCHEMBL9991447 | 0.76 | — | — | |
| SCHEMBL3292258 | 0.76 | — | — | |
| SCHEMBL28635110 | 0.75 | ALDH1A1 (0.34) | KDM4EHPGDALDH1A1MAPTCYP3A4 | |
| SCHEMBL27698046 | 0.75 | ALDH1A1 (0.34) | KDM4EHPGDALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274721-B1 | POLYMERS CONTAINING AMINO GROUPS, THEIR MANUFACTURE AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0274721-A2 | Polymers containing amino groups, their manufacture and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-20 | — | — | EP | disclosed |