Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27054138 | 0.97 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| Iodide SCHEMBL10703817 | 0.97 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL19634654 | 0.97 | SIGMAR1 (0.39) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL10370166 | 0.91 | — | — | |
| SCHEMBL15052279 | 0.84 | SIGMAR1 (0.48) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL234338 | 0.84 | SIGMAR1 (0.48) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL2564528 | 0.81 | SIGMAR1 (0.46) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL2142541 | 0.81 | SIGMAR1 (0.46) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL2137948 | 0.81 | SIGMAR1 (0.46) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 | |
| SCHEMBL1313942 | 0.81 | SIGMAR1 (0.46) | SIGMAR1HRH4HRH3SLC2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646043-B1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL INC (US) | 2017-02-15 | — | — | EP | disclosed |
| WO-2015196072-A2 | USES OF KINASE INHIBITORS FOR INDUCING AND MAINTAINING PLURIPOTENCY | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-12-23 | — | — | WO | disclosed |
| EP-0331472-B1 | Dialkylaminoalkyl-hydroxyalkyl ethers of polygalactomannans | STEIN HALL & CO INC (US) | 1993-11-03 | — | — | EP | disclosed |
| US-4941537-A | ADDING ALKALI METAL OR ALKALINE METAL HYPOCHLOROUS ACID SALTS OR CHLORINATED ISOCYANURATES TO THIN TERT-AMINO POLYGALACTOMAN NANS | HI-TEK POLYMERS, INC. (US) | 1990-07-17 | — | — | US | disclosed |
| US-4918181-A | Tertiaryaminoalkyl-hydroxyalkyl ethers of polygalactomannans | RHODIA INC. | 1990-04-17 | — | — | US | disclosed |
| EP-0331472-A2 | Dialkylaminoalkyl-hydroxyalkyl ethers of polygalactomannans | STEIN, HALL & CO., INC. (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0330489-A2 | Method for reducing the viscosity of aqueous fluids | STEIN, HALL & CO., INC. (US) | 1989-08-30 | — | — | EP | disclosed |