Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511890 | 0.82 | TMEM97 (0.61) | TMEM97SIGMAR1TBXA2RALDH1A1TP53 | |
| SCHEMBL566005 | 0.81 | TSHR (0.61) | TMEM97SIGMAR1TBXA2RALDH1A1TP53 | |
| SCHEMBL9870095 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9872413 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9870233 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9869922 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9879916 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9871736 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9872542 | 0.77 | TBXA2R (0.75) | TBXA2RALDH1A1TP53GAAFABP4 | |
| SCHEMBL9577200 | 0.76 | ALDH1A1 (0.68) | TMEM97SIGMAR1ALDH1A1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353448-B1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-27 | — | — | EP | disclosed |
| US-4981873-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-01 | — | — | US | disclosed |