SCHEMBL9511995

SCHEMBL9511995

CC1OC1(C(=O)OCCOC(=O)C1(c2ccccc2)OC1C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 3/20 0.41
APOBEC3A P31941 3/20 0.40
APOBEC3G Q9HC16 3/20 0.40
PRCP P42785 2/20 0.40
SIGMAR1 Q99720 2/20 0.40
CHRM1 P11229 3/20 0.39
CHRM2 P08172 2/20 0.39
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
SLC22A1 O15245 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
THRB P10828 1/20 0.39
TMEM97 Q5BJF2 1/20 0.39
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57715 0.89 OPRM1 (0.49) TSHRCYP2C19SLC22A1CYP1A2CYP2D6
Acetophenone SCHEMBL9805913 0.82 TSHR (0.39) ALDH1A1LMNATSHRCYP3A4TDP1
SCHEMBL329170 0.78 AKR1C1 (0.39) ALDH1A1LMNAHTTCHRM1CHRM2
SCHEMBL14967636 0.76 LMNA (0.43) ALDH1A1LMNATSHRPRCPSIGMAR1
SCHEMBL17267397 0.75 OPRM1 (0.47) LMNAHTTGAAMEN1KMT2A
SCHEMBL14967448 0.75 TSHR (0.44) ALDH1A1LMNATSHRCYP2C19SIGMAR1
SCHEMBL27936152 0.74 OPRM1 (0.48) TSHRSLC22A1OPRM1
SCHEMBL14968205 0.74 PPARG (0.48) ALDH1A1LMNATSHRSIGMAR1CHRM1
SCHEMBL28994067 0.73 OPRM1 (0.47) TSHRSLC22A1GAAOPRM1
SCHEMBL14968247 0.73 PPARG (0.50) ALDH1A1LMNATSHRCYP2C19SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347227-B1 Pesticidal compositions DU PONT (US) 1993-11-24 EP disclosed
US-5135744-A PALATABLE SOLID PESTICIDAL COMPOSITIONS OF ETHYLENE AND VINYL ACETATE COPOLYMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-04 US disclosed
EP-0347227-A1 Pesticidal compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-12-20 EP disclosed