Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512215 | 1.00 | APP (0.60) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL9512194 | 0.99 | APP (0.63) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL9512198 | 0.99 | APP (0.63) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL9512190 | 0.99 | APP (0.63) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL9787348 | 0.99 | APP (0.63) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL8422918 | 0.94 | PTGS2 (0.51) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL8645474 | 0.94 | PTGS2 (0.51) | APPFBP1PTGS2PTGS1MAOB | |
| SCHEMBL168393 | 0.87 | ALDH1A1 (0.54) | MAPTALDH1A1POLBGAAMEN1 | |
| SCHEMBL531065 | 0.86 | ALDH1A1 (0.55) | APPFBP1PTGS2PTGS1MAPT | |
| SCHEMBL531064 | 0.86 | ALDH1A1 (0.55) | APPFBP1PTGS2PTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350112-B1 | POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| US-5001209-A | Non-linear optical active diols and polyurethanes prepared therefrom | AKZO N.V. (NL) | 1991-03-19 | — | — | US | disclosed |
| EP-0350112-A1 | Polyurethanes prepared from non-linear optical active diols | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |