Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515501 | 0.92 | RARB (0.48) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9513283 | 0.91 | RARB (0.53) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9513219 | 0.89 | RARB (0.55) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9511789 | 0.89 | RARB (0.55) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9062036 | 0.88 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9513537 | 0.88 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9062438 | 0.87 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9061908 | 0.84 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9515504 | 0.83 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9515537 | 0.83 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387315-B1 | FLUORINATED ALKOXYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |