Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512236 | 0.88 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9061744 | 0.88 | RXRA (0.49) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9060183 | 0.86 | GRIN1 (0.48) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9515501 | 0.86 | RARB (0.48) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9513283 | 0.85 | RARB (0.53) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9513219 | 0.84 | RARB (0.55) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9511789 | 0.84 | RARB (0.55) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9060293 | 0.82 | RXRA (0.46) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9515504 | 0.82 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9515537 | 0.82 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387315-B1 | FLUORINATED ALKOXYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |