Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512280 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53CASP3SENP8 | |
| SCHEMBL9512266 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNATP53CASP3SENP8 | |
| SCHEMBL9510602 | 0.83 | HPGD (0.47) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL9510511 | 0.83 | HPGD (0.47) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL9512111 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL9512116 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL9510513 | 0.83 | HPGD (0.47) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL9510864 | 0.79 | TSHR (0.51) | ALDH1A1LMNATP53CASP3SENP8 | |
| SCHEMBL9510853 | 0.79 | TSHR (0.51) | ALDH1A1LMNATP53CASP3SENP8 | |
| SCHEMBL9512853 | 0.76 | TSHR (0.53) | ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569409-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-11-18 | — | — | EP | claimed |
| WO-1992012959-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-06 | — | — | WO | claimed |
| EP-0569409-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012959-A1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-06 | — | — | WO | disclosed |