Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906310 | 0.89 | PAM (0.56) | CYP3A4NPSR1SMN1; SMN2PKMLMNA | |
| SCHEMBL6746074 | 0.79 | TDP1 (0.45) | CYP3A4SMN1; SMN2LMNAKDM4EPAM | |
| SCHEMBL6746075 | 0.79 | TDP1 (0.45) | CYP3A4SMN1; SMN2LMNAKDM4EPAM | |
| SCHEMBL7265789 | 0.79 | APP (0.51) | CYP3A4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL11274669 | 0.78 | CYP4F2 (0.51) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL11274670 | 0.78 | CYP4F2 (0.51) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL11765846 | 0.78 | PAM (0.61) | SMN1; SMN2LMNAMAPTPAMMAOB | |
| SCHEMBL23392491 | 0.78 | PKM (0.54) | CYP3A4NPSR1SMN1; SMN2PKMLMNA | |
| SCHEMBL11765851 | 0.77 | PAM (0.47) | CYP3A4SMN1; SMN2PKMLMNAMEN1 | |
| SCHEMBL3360904 | 0.76 | PAM (0.57) | SMN1; SMN2LMNAMAPTMAPK1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350878-B1 | Conjugated gamma-oxybutenolide compounds for treating ulcer | KURARAY CO (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-4950818-A | 5-hydroxy-4-(2-phenyl-ce)-ethenyl)-2(5h)-furanone compounds | KURARAY COMPANY, LTD. (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0350878-A2 | Conjugated gamma-oxybutenolide compounds for treating ulcer | KURARAY CO., LTD. (JP) | 1990-01-17 | — | — | EP | disclosed |