Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512333 | 0.96 | DRD2 (0.49) | MCHR1DRD2APPACACBGRM3 | |
| SCHEMBL11282461 | 0.91 | DRD2 (0.53) | DRD2DGAT1MEN1ALDH1A1MAPK1 | |
| SCHEMBL9509299 | 0.89 | DRD2 (0.47) | MCHR1DRD2APPDGAT1MEN1 | |
| SCHEMBL9510136 | 0.89 | ACACB (0.50) | MCHR1ACACBDGAT1 | |
| SCHEMBL9509338 | 0.87 | DRD2 (0.45) | MCHR1DRD2APPDGAT1MEN1 | |
| SCHEMBL10017476 | 0.87 | DRD2 (0.57) | DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9510031 | 0.86 | ACACB (0.44) | MCHR1ACACBALDH1A1 | |
| SCHEMBL9508782 | 0.86 | RAB9A (0.46) | MCHR1ACACB | |
| SCHEMBL10510487 | 0.86 | MCHR1 (0.44) | MCHR1DRD2ACACBALDH1A1 | |
| SCHEMBL9742421 | 0.85 | SLC6A2 (0.45) | DRD2APPACACBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |