Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512534 | 0.99 | CNR2 (0.42) | CNR2NR5A1CYSLTR2CYSLTR1LTA4H | |
| SCHEMBL9511360 | 0.97 | ACACB (0.41) | CNR2NR5A1CYSLTR2CYSLTR1ACACB | |
| SCHEMBL9512289 | 0.96 | ACACB (0.39) | CNR2NR5A1CYSLTR2CYSLTR1ACACB | |
| SCHEMBL9512387 | 0.93 | ACACB (0.41) | ACACBCYP3A4CYP2D6MCHR1 | |
| SCHEMBL9510227 | 0.93 | NR5A1 (0.41) | CNR2NR5A1CYSLTR2CYSLTR1ACACB | |
| SCHEMBL9508900 | 0.93 | MAPT (0.41) | CNR2CYSLTR2CYSLTR1ACACBL3MBTL1 | |
| SCHEMBL9510156 | 0.93 | ACACB (0.39) | NR5A1CYSLTR2CYSLTR1ACACBLTA4H | |
| SCHEMBL10509743 | 0.93 | CYSLTR2 (0.37) | CNR2CYSLTR2CYSLTR1ACACB | |
| SCHEMBL10519853 | 0.91 | ACACB (0.39) | CYSLTR2CYSLTR1ACACB | |
| SCHEMBL9509991 | 0.91 | APP (0.40) | CYSLTR2CYSLTR1CYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |