Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 14/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512376 | 0.96 | ACACB (0.39) | MAPTRAB9AL3MBTL1ACACBNQO1 | |
| SCHEMBL9512426 | 0.93 | CNR2 (0.40) | L3MBTL1ACACBCNR2CYSLTR2CYSLTR1 | |
| SCHEMBL10511640 | 0.93 | MAPT (0.37) | MAPTRAB9AL3MBTL1ACACBTSHR | |
| SCHEMBL9512534 | 0.92 | CNR2 (0.42) | L3MBTL1CNR2CYSLTR2CYSLTR1 | |
| SCHEMBL9511360 | 0.91 | ACACB (0.41) | ACACBCNR2CYSLTR2CYSLTR1 | |
| SCHEMBL9508844 | 0.91 | ACACB (0.40) | ACACBNQO1 | |
| SCHEMBL9509991 | 0.90 | APP (0.40) | MAPTTSHRCYSLTR2CYSLTR1 | |
| SCHEMBL9512289 | 0.89 | ACACB (0.39) | L3MBTL1ACACBCNR2CYSLTR2CYSLTR1 | |
| SCHEMBL10302771 | 0.89 | FFAR4 (0.38) | MAPTRAB9AL3MBTL1ACACBCNR2 | |
| SCHEMBL9510227 | 0.87 | NR5A1 (0.41) | L3MBTL1ACACBCNR2TSHRCYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |