Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628197 | 1.00 | MAPT (0.52) | MAPTHSD17B10MAPK1PKMELANE | |
| SCHEMBL9512465 | 0.87 | MAPT (0.69) | MAPTHSD17B10ELANEADRB2ADRB1 | |
| SCHEMBL10423302 | 0.85 | HSD17B10 (0.50) | MAPTHSD17B10MAPK1PKMELANE | |
| SCHEMBL9579629 | 0.83 | ELANE (0.54) | MAPTHSD17B10MAPK1PKMELANE | |
| SCHEMBL10423598 | 0.83 | HSD17B10 (0.58) | MAPTHSD17B10MAPK1PKMELANE | |
| SCHEMBL10422606 | 0.83 | MAPT (0.64) | MAPTHSD17B10ELANEADRB2ADRB1 | |
| SCHEMBL9627889 | 0.82 | ESR1 (0.60) | MAPTHSD17B10MAPK1PKMADRB2 | |
| SCHEMBL9627881 | 0.82 | ESR1 (0.60) | MAPTHSD17B10MAPK1PKMADRB2 | |
| SCHEMBL14399226 | 0.81 | KMT2A (0.46) | MAPTHSD17B10MAPK1PKMELANE | |
| SCHEMBL9446645 | 0.80 | LMNA (0.57) | MAPTHSD17B10MAPK1ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311257-B1 | CHOLESTERIC LIQUID CRYSTAL POLYESTERS | NIPPON OIL CO. LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4891418-A | MELT PROCESSABILITY | NIPPON OIL COMPANY, LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0311257-A1 | Cholesteric liquid crystal polyesters | NIPPON OIL CO. LTD. (JP) | 1989-04-12 | — | — | EP | disclosed |
| US-4746722-A | HIGH STRENGTH AND MODULUS, REDUCED ANISOTROPY | NIPPON OIL COMPANY, LIMITED (JP) | 1988-05-24 | — | — | US | disclosed |
| EP-0251688-A2 | Cholesteric liquid crystal polyesters | NIPPON OIL CO. LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |