⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1457573 | 0.84 | — | — | |
| SCHEMBL1448081 | 0.70 | — | — | |
| SCHEMBL3126263 | 0.70 | — | — | |
| SCHEMBL16986050 | 0.70 | — | — | |
| SCHEMBL10969487 | 0.64 | — | — | |
| SCHEMBL9600805 | 0.64 | — | — | |
| SCHEMBL8347906 | 0.64 | — | — | |
| SCHEMBL2491334 | 0.64 | — | — | |
| SCHEMBL158499 | 0.64 | — | — | |
| SCHEMBL10818184 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63017859-A | — | — | None | — | — | JP | disclosed |
| EP-2814825-B1 | DIHYDROFURAN AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9133172-B2 | Dihydrofuran azetidine derivatives as antiparasitic agents | ZOETIS SERVICES LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-20150038440-A1 | DIHYDROFURAN AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2015-02-05 | — | — | US | disclosed |
| EP-2814825-A1 | DIHYDROFURAN AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2014-12-24 | — | — | EP | disclosed |
| WO-2013116230-A1 | DIHYDROFURAN AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-0256763-B1 | Process for azetidinones | UNIV NOTRE DAME DU LAC (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0154132-B1 | 6-ALKYLIDENE PENEMS, THEIR PREPARATION AND USE, AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1992-01-08 | — | — | EP | disclosed |
| EP-0451764-A1 | Carbapenem compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |
| WO-1987000525-A1 | 6-ALKYLIDENE PENEMS | BEECHAM GROUP P.L.C. (GB) | 1987-01-29 | — | — | WO | disclosed |
| EP-0088488-B1 | ANTIBACTERIAL AGENTS, THEIR PREPARATION AND USE | BEECHAM GROUP PLC (GB) | 1986-10-01 | — | — | EP | disclosed |
| EP-0095778-B1 | 2-OXO-1-AZETIDINESULFONIC ACID DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |
| EP-0150781-A1 | 6-Alkylidene pemens, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-08-07 | — | — | EP | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |
| EP-0095778-A1 | 2-Oxo-1-azetidinesulfonic acid derivatives, process for production thereof, and use thereof | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-12-07 | — | — | EP | disclosed |
| EP-0088488-A1 | Antibacterial agents, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-09-14 | — | — | EP | disclosed |
| US-4108992-A | BACTERICIDES | BEECHAM GROUP LIMITED (GB) | 1978-08-22 | — | — | US | disclosed |