⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14331814 | 0.84 | — | — | |
| SCHEMBL9512592 | 0.64 | — | — | |
| SCHEMBL2491334 | 0.64 | — | — | |
| SCHEMBL8347906 | 0.64 | — | — | |
| SCHEMBL158499 | 0.64 | — | — | |
| SCHEMBL9600805 | 0.64 | — | — | |
| SCHEMBL9760607 | 0.58 | — | — | |
| SCHEMBL32665757 | 0.57 | — | — | |
| SCHEMBL32665756 | 0.57 | — | — | |
| SCHEMBL2809033 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371464-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2014-12-18 | — | — | US | disclosed |
| EP-2809667-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116236-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-0060119-B1 | AZETIDINONE COMPOUNDS AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4500456-A | AND AZETIDINONE-4-SULFINIC ACID, OR SALT THEREOF | ELI LILLY AND COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0060119-A1 | Azetidinone compounds and their preparation | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |