⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10524099 | 0.81 | — | — | |
| SCHEMBL8347906 | 0.64 | — | — | |
| SCHEMBL9512592 | 0.64 | — | — | |
| SCHEMBL9600805 | 0.64 | — | — | |
| SCHEMBL158499 | 0.64 | — | — | |
| SCHEMBL10969487 | 0.64 | — | — | |
| SCHEMBL11232891 | 0.62 | — | — | |
| SCHEMBL9760607 | 0.58 | — | — | |
| SCHEMBL14698534 | 0.55 | — | — | |
| SCHEMBL2809033 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2000-11-29 | — | — | EP | claimed |
| WO-1999040091-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 1999-08-12 | — | — | WO | claimed |
| US-3957771-A | PHOSPHINIC ACID CHLORIDES, ALCOHOLS, HYDROLYSIS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | claimed |
| US-8324198-B1 | Monocarbams | PFIZER INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120289455-A1 | Monocarbams | PFIZER INC. | 2012-11-15 | — | — | US | disclosed |
| US-8252782-B2 | Monocarbams | PFIZER INC. (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2379546-A1 | MONOCARBAMS | Pfizer Inc. (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010070523-A1 | MONOCARBAMS | PFIZER INC. (US) | 2010-06-24 | — | — | WO | disclosed |
| US-20100160281-A1 | MONOCARBAMS | PFIZER INC | 2010-06-24 | — | — | US | disclosed |
| EP-0920527-B1 | SYNTHESIS OF beta-LACTAM ANTIBACTERIALS USING SOLUBLE SIDE CHAIN ESTERS AND ENZYME ACYLASE | BRISTOL MYERS SQUIBB CO (US) | 2008-03-19 | — | — | EP | disclosed |
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-0209352-A2 | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0187500-A1 | Monobactams | THE UPJOHN COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0163452-A1 | A novel process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones | ELI LILLY AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |
| EP-0060119-B1 | AZETIDINONE COMPOUNDS AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4500456-A | AND AZETIDINONE-4-SULFINIC ACID, OR SALT THEREOF | ELI LILLY AND COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0060119-A1 | Azetidinone compounds and their preparation | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4085100-A | Intermediate for dephthaloylation of azetidinone compounds | SMITHKLINE CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4085100-A | Intermediate for dephthaloylation of azetidinone compounds | SMITHKLINE CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-3957771-A | PHOSPHINIC ACID CHLORIDES, ALCOHOLS, HYDROLYSIS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |