Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245384 | 0.82 | IAPP (0.39) | IAPPTRPA1CES2CES1FFAR3 | |
| SCHEMBL11245383 | 0.82 | IAPP (0.39) | IAPPTRPA1CES2CES1FFAR3 | |
| SCHEMBL7941358 | 0.78 | ALDH1A1 (0.37) | EGFRALDH1A1 | |
| SCHEMBL7941360 | 0.78 | ALDH1A1 (0.37) | EGFRALDH1A1 | |
| SCHEMBL10871127 | 0.75 | CES2 (0.50) | IAPPTRPA1CES2CES1FFAR3 | |
| SCHEMBL10871136 | 0.75 | CES2 (0.50) | IAPPTRPA1CES2CES1FFAR3 | |
| SCHEMBL6722055 | 0.75 | — | — | |
| SCHEMBL1156682 | 0.75 | — | — | |
| SCHEMBL2592835 | 0.75 | — | — | |
| SCHEMBL18753087 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081310-A | PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-01-14 | — | — | US | claimed |
| EP-0409530-B1 | Catalytic preparation of optically active ketones | TAKASAGO PERFUMERY CO LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5081310-A | PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-01-14 | — | — | US | disclosed |