SCHEMBL9512923

SCHEMBL9512923

O=C1c2ccc(N3CCCC3)cc2-c2cc(N3CCCC3)ccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
MAPT P10636 4/20 0.61
L3MBTL1 Q9Y468 4/20 0.61
HSD17B10 Q99714 2/20 0.61
MEN1 O00255 2/20 0.61
ALOX15 P16050 2/20 0.61
KMT2A Q03164 2/20 0.61
LMNA P02545 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TERT O14746 2/20 0.47
HSP90AA1 P07900 1/20 0.47
CCR6 P51684 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
PSMD14 O00487 1/20 0.46
MAPK1 P28482 2/20 0.46
PTGS2 P35354 2/20 0.46
ACHE P22303 1/20 0.46
EGFR P00533 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29204334 0.91 ALDH1A1 (0.61) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
Hydrochloric Acid SCHEMBL11750895 0.90 ALDH1A1 (0.56) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
SCHEMBL14983932 0.90 ALDH1A1 (0.56) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
Hydrochloric Acid SCHEMBL11750902 0.90 ALDH1A1 (0.56) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
SCHEMBL14983928 0.88 ALDH1A1 (0.54) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
SCHEMBL5631829 0.88 ALDH1A1 (0.54) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
SCHEMBL9244107 0.84 ALDH1A1 (0.50) ALDH1A1MAPTL3MBTL1HSD17B10MEN1
SCHEMBL14983921 0.80 PSMD14 (0.60) ALDH1A1MAPTL3MBTL1MEN1KMT2A
SCHEMBL14983919 0.80 PSMD14 (0.60) ALDH1A1MAPTL3MBTL1MEN1KMT2A
SCHEMBL10689686 0.78 ALDH1A1 (0.56) ALDH1A1MAPTL3MBTL1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed