Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512985 | 0.85 | TRPA1 (0.41) | BHMTGAAMGAMSIMGAM2 | |
| SCHEMBL13399149 | 0.82 | GAA (0.44) | CYP4F2CYP4A11TDP1GAAMGAM | |
| SCHEMBL7668564 | 0.80 | GAA (0.50) | CYP4F2CYP4A11TDP1GAAMGAM | |
| SCHEMBL22070619 | 0.79 | CYP4F2 (0.53) | CYP4F2CYP4A11TDP1GAAMGAM | |
| SCHEMBL4996013 | 0.78 | GAA (0.48) | CYP4F2CYP4A11TDP1GAAMGAM | |
| SCHEMBL9514299 | 0.76 | CYP4F2 (0.59) | CYP4F2CYP4A11TDP1ABL1RIN1 | |
| SCHEMBL232993 | 0.75 | GAA (0.55) | CYP4F2CYP4A11GAAMGAMSI | |
| SCHEMBL10890422 | 0.75 | GBA1 (0.40) | BHMTGAAMGAMSIMGAM2 | |
| SCHEMBL2991171 | 0.74 | TDP1 (0.54) | CYP4F2CYP4A11TDP1GAAMGAM | |
| SCHEMBL13901847 | 0.74 | TDP1 (0.48) | CYP4F2CYP4A11TDP1ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353448-B1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-27 | — | — | EP | disclosed |
| US-4981873-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-01 | — | — | US | disclosed |
| EP-0353448-A1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | Roche Diagnostics GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |