Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514301 | 0.90 | CYP4F2 (0.65) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL9515174 | 0.84 | CYP4F2 (0.49) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL6410664 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL1723361 | 0.81 | CYP4F2 (0.71) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL15945347 | 0.79 | CYP4F2 (0.64) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL2021436 | 0.78 | CYP4F2 (0.67) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL3289027 | 0.77 | CYP4F2 (0.92) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL1164946 | 0.76 | CYP4F2 (0.59) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL9512942 | 0.76 | BHMT (0.39) | CYP4F2CYP4A11TDP1HTTABL1 | |
| SCHEMBL4100758 | 0.76 | CYP4F2 (0.96) | CYP4F2CYP4A11PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353448-B1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-27 | — | — | EP | disclosed |
| US-4981873-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-01 | — | — | US | disclosed |
| EP-0353448-A1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | Roche Diagnostics GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |