Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL748244 | 0.98 | TSHR (0.37) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL15053822 | 0.98 | TSHR (0.37) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL8727210 | 0.98 | TSHR (0.37) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL15308 | 0.98 | TSHR (0.37) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Methyl Alcohol SCHEMBL9400635 | 0.95 | TSHR (0.35) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Ethane SCHEMBL10522900 | 0.95 | TSHR (0.35) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Methane SCHEMBL2179835 | 0.95 | TSHR (0.35) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Ammonia Solution, Strong SCHEMBL9513085 | 0.95 | TSHR (0.35) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Fluoride SCHEMBL6427102 | 0.95 | TSHR (0.35) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL7262572 | 0.95 | TSHR (0.35) | TSHRALDH1A1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118336122-A | Electrolyte and sodium ion battery for stabilizing lamellar positive electrode by synergistic action of nitrile cosolvent and double salts | 河北工业大学 | 2024-07-12 | — | — | CN | claimed |
| EP-4398365-A1 | LITHIUM ION SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE SOLUTION | Kyocera Corporation (JP) | 2024-07-10 | — | — | EP | claimed |
| CN-117936751-A | Potassium-based layered oxide positive electrode material and preparation method and application thereof | 西安交通大学 | 2024-04-26 | — | — | CN | claimed |
| CN-114456356-B | Polyperylene tetracarboxylic diimide, preparation method thereof and application thereof in lithium/sodium battery | 郑州大学 | 2023-06-20 | — | — | CN | claimed |
| CN-114479078-B | Naphthalimide polymer, preparation method thereof and application thereof in lithium/sodium battery | 郑州大学 | 2023-04-25 | — | — | CN | claimed |
| US-20220336863-A1 | RECHARGEABLE CALCIUM BATTERY | SYRACUSE UNIVERSITY (US) | 2022-10-20 | — | — | US | claimed |
| CN-113346131-B | Composite polymer gel solid electrolyte, preparation method thereof and application of lithium metal battery | 北京理工大学 | 2022-08-30 | — | — | CN | claimed |
| US-11355774-B2 | Thermally-drawn fiber including electrochemically active gels | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-06-07 | — | — | US | claimed |
| CN-114456356-A | Poly (perylene) tetracarboxydiimide, preparation method thereof and application thereof in lithium/sodium battery | 郑州大学 | 2022-05-10 | — | — | CN | claimed |
| CN-113346131-A | Composite polymer gel solid electrolyte, preparation method thereof and application of lithium metal battery | 北京理工大学 | 2021-09-03 | — | — | CN | claimed |
| CN-101752090-B | Polyionic liquid base micropore quasi solid state electrolyte preparation method and application | UNIV NANJING AERONAUTICS | 2011-08-10 | — | — | CN | claimed |
| US-20110026189-A1 | Single-wall Carbon Nanotube Supercapacitor | UNIVERSITY OF DELAWARE (US) | 2011-02-03 | — | — | US | claimed |
| CN-101752090-A | Polyionic liquid base micropore quasi solid state electrolyte preparation method and application | UNIV NANJING AERONAUTICS | 2010-06-23 | — | — | CN | claimed |
| US-20080118455-A1 | ALKYLENE CARBONATE DILUTION, ALKYLENE CARBONATE FOR PREPARING THE DILUTION, AND AQUEOUS REDUCING CHEMICAL AGENT | SAN-EI KAGAKU CO., LTD. (JP) | 2008-05-22 | — | — | US | claimed |
| US-7150941-B2 | High energy density power sources comprising electrolytes, anodes, and cathodes capable of reversible occlusion and releasing lithium precipitates on the electrode; charging and discharging efficiency | SONY CORPORATION (JP) | 2006-12-19 | — | — | US | claimed |
| US-20050164087-A1 | Secondary battery | FUJITA SHIGERU (JP) | 2005-07-28 | — | — | US | claimed |
| US-6884546-B1 | Secondary battery | SONY CORPORATION (JP) | 2005-04-26 | — | — | US | claimed |
| EP-1137092-A1 | SECONDARY CELL | Sony Corporation (JP) | 2001-09-26 | — | — | EP | claimed |
| CN-1013422-B | NON-AQUEOUS SECONDARY CELL | SHOWA DENKO KK (JP) | 1991-07-31 | — | — | CN | claimed |
| CN-88101323-A | NON-AQUEOUS SECONDARY CELL | — | 1988-11-09 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080118455-A1 | ALKYLENE CARBONATE DILUTION, ALKYLENE CARBONATE FOR PREPARING THE DILUTION, AND AQUEOUS REDUCING CHEMICAL AGENT | AXIN2, WNT1, MGMT | TSHR 3924/4885ALDH1A1 877/4885CHRM2 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.