Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513432 | 0.81 | FAAH (0.46) | FAAHCES1FDPSSIGMAR1GGPS1 | |
| SCHEMBL193529 | 0.76 | LPAR1 (0.58) | PNPFDPSGGPS1 | |
| SCHEMBL14890455 | 0.74 | CETP (0.50) | SIGMAR1 | |
| SCHEMBL1527593 | 0.73 | PNP (0.42) | PNP | |
| SCHEMBL7331812 | 0.72 | CETP (0.47) | — | |
| SCHEMBL17772828 | 0.72 | NPSR1 (0.44) | FDPSNPSR1 | |
| SCHEMBL11652128 | 0.72 | CETP (0.51) | SIGMAR1 | |
| SCHEMBL1527573 | 0.72 | PNP (0.40) | PNP | |
| SCHEMBL8816751 | 0.71 | FAAH (0.50) | FAAHCES1NPSR1 | |
| SCHEMBL8818978 | 0.71 | FAAH (0.50) | FAAHCES1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338887-B1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMA (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4988680-A | Phosphorylase inhibitors, immuno suppressants, parasiticides, antileukemia agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-29 | — | — | US | disclosed |