Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | FDPS | P14324 | 6/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513451 | 0.81 | PNP (0.47) | FAAHCES1FDPSGGPS1PTPN2 | |
| SCHEMBL22296453 | 0.74 | FAAH (0.51) | FAAHCES1SIGMAR1MAPTRXFP1 | |
| SCHEMBL28037433 | 0.74 | FAAH (0.55) | FAAHCES1SIGMAR1MAPTRXFP1 | |
| SCHEMBL31038120 | 0.74 | FAAH (0.55) | FAAHCES1SIGMAR1MAPTRXFP1 | |
| SCHEMBL28303524 | 0.72 | FAAH (0.49) | FAAHCES1SIGMAR1 | |
| SCHEMBL9192045 | 0.72 | MAOA (0.52) | FAAHCES1SIGMAR1MAPTRXFP1 | |
| SCHEMBL17288469 | 0.71 | FAAH (0.51) | FAAHCES1SIGMAR1MAPTRXFP1 | |
| SCHEMBL17288637 | 0.71 | FAAH (0.51) | FAAHCES1SIGMAR1MAPTRXFP1 | |
| SCHEMBL8814986 | 0.70 | FAAH (0.60) | FAAHCES1MAPTRXFP1MAPK1 | |
| SCHEMBL8817760 | 0.70 | FAAH (0.60) | FAAHCES1MAPTRXFP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338887-B1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMA (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4988680-A | Phosphorylase inhibitors, immuno suppressants, parasiticides, antileukemia agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0338168-A1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338887-A1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-10-25 | — | — | EP | disclosed |