Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513989 | 0.86 | PPOX (0.37) | PPOXP2RX3 | |
| SCHEMBL9513998 | 0.85 | PPOX (0.37) | PPOXP2RX3 | |
| SCHEMBL7891230 | 0.84 | PPOX (0.45) | PPOXGRM1GRM7GRM4 | |
| SCHEMBL10513071 | 0.83 | PPOX (0.52) | PPOXGRM1GRM7GRM4 | |
| SCHEMBL7891045 | 0.81 | PPOX (0.51) | PPOXGRM1GRM7GRM4 | |
| SCHEMBL8084286 | 0.81 | PPOX (0.69) | PPOX | |
| SCHEMBL7652449 | 0.81 | GRM7 (0.42) | GRM1GRM7GRM4 | |
| SCHEMBL9514181 | 0.80 | GRM7 (0.40) | GRM1GRM7GRM4 | |
| SCHEMBL9513988 | 0.79 | BCAT2 (0.36) | PPOXP2RX3 | |
| SCHEMBL9387865 | 0.79 | PPOX (0.41) | PPOXGRM1GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303573-B1 | PYRROLIDINE-2,5 DIONES AND 4,5,6,7-TETRAHYDROISO-INDOLE-1,3 DIONES | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | claimed |
| US-4919704-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | claimed |
| EP-0303573-B1 | PYRROLIDINE-2,5 DIONES AND 4,5,6,7-TETRAHYDROISO-INDOLE-1,3 DIONES | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-4919704-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | disclosed |