Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711216 | 0.91 | FFAR1 (0.47) | PTGDR2FFAR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9514097 | 0.91 | FFAR1 (0.50) | FFAR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10704116 | 0.88 | PTGDR2 (0.48) | PTGDR2FFAR1 | |
| SCHEMBL9510498 | 0.83 | ADRB2 (0.52) | ALDH1A1NPSR1 | |
| SCHEMBL9510541 | 0.80 | TBXA2R (0.59) | ALDH1A1 | |
| SCHEMBL9510778 | 0.79 | PTGDR2 (0.51) | PTGDR2TSHRTDP1 | |
| SCHEMBL9765285 | 0.79 | KDM4E (0.53) | PTGDR2ALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL9765309 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL27672375 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2NPSR1TSHR | |
| SCHEMBL9510759 | 0.74 | POLB (0.47) | ALDH1A1LMNASMN1; SMN2NPSR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | claimed |
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |