SCHEMBL9514240

SCHEMBL9514240

Cc1cn([C@H]2C[C@H](N)[C@@H](CC(=O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TK1 P04183 4/20 0.55
RNASE1 P07998 1/20 0.54
ALB P02768 1/20 0.53
PKM P14618 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514246 1.00 TK1 (0.55) TK1RNASE1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL1415407 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL17011263 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL9484283 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL1415408 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL20099120 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL13394196 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL19831521 0.87 TK1 (0.68) TK1ALBPKM
3-Amino- 3-Deoxythymidine SCHEMBL13497992 0.87 TK1 (0.68) TK1ALBPKM
SCHEMBL8780256 0.87 TK1 (0.56) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565646-A1 NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME BAYLOR COLLEGE OF MEDICINE (US) 1993-10-20 EP disclosed
US-5175266-A Oxidizing hydroxymethyl function of azidodeoxynucleosides to acid in presence of ruthenium tetroxide TRIPLEX PHARMACEUTICAL CORPORATION (US) 1992-12-29 US disclosed
WO-1992018518-A1 NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME BAYLOR COLLEGE OF MEDICINE (US) 1992-10-29 WO disclosed