Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514462 | 1.00 | CYP19A1 (0.45) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL9514456 | 0.84 | LCK (0.45) | MAOANPC1MAPTNPSR1KDM1A | |
| SCHEMBL9514452 | 0.84 | LCK (0.45) | MAOANPC1MAPTNPSR1KDM1A | |
| SCHEMBL9516857 | 0.83 | CYP19A1 (0.50) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL9516867 | 0.83 | CYP19A1 (0.50) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL9515945 | 0.70 | MAPT (0.55) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL9515936 | 0.70 | MAPT (0.55) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL5775979 | 0.70 | NPC1 (0.48) | CYP19A1MAOAMAOBNPC1MAPT | |
| SCHEMBL6584167 | 0.70 | RAB9A (0.41) | NPC1MAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL2774526 | 0.70 | CYP19A1 (0.86) | CYP19A1MAOAMAOBNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |