Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | INSR | P06213 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515945 | 1.00 | MAPT (0.55) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9335180 | 0.83 | KAT8 (0.50) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9335185 | 0.83 | KAT8 (0.50) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2628251 | 0.83 | MEN1 (0.67) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1242918 | 0.83 | MEN1 (0.67) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL537848 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL31063726 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL537849 | 0.82 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9514854 | 0.82 | SNCA (0.64) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9514858 | 0.82 | SNCA (0.64) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |