Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL28195898 | 0.95 | — | — | |
| Tetramethylammonium Ion SCHEMBL28232298 | 0.90 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4NFKB1 | |
| Ethylenediamine SCHEMBL28149523 | 0.78 | — | — | |
| Ethylenediamine SCHEMBL27600441 | 0.78 | — | — | |
| Ethylenediamine SCHEMBL16863035 | 0.78 | — | — | |
| Tetramethylammonium Ion SCHEMBL28044151 | 0.76 | NFKB1 (0.50) | CHRNB2CHRNA7CHRNA4NFKB1 | |
| Ethylenediamine SCHEMBL8473348 | 0.72 | — | — | |
| Ethylenediamine SCHEMBL9568006 | 0.72 | — | — | |
| Ethylenediamine SCHEMBL28924405 | 0.71 | NFKB1 (0.50) | NFKB1 | |
| Ethylenediamine SCHEMBL37647 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408205-B1 | Polyimide substrate having a textured surface metallizing such a substrate | MINNESOTA MINING & MFG (US) | 1993-12-15 | — | — | EP | disclosed |
| EP-0408205-A1 | Polyimide substrate having a textured surface metallizing such a substrate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-01-16 | — | — | EP | disclosed |
| US-4975327-A | SURFACE RECESSES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-04 | — | — | US | disclosed |