Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515570 | 0.85 | TARBP2 (0.73) | TARBP2POLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL17714990 | 0.84 | TARBP2 (0.48) | TARBP2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL17714981 | 0.84 | TARBP2 (0.60) | TARBP2POLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL17714988 | 0.84 | TARBP2 (0.48) | TARBP2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL17715247 | 0.83 | TARBP2 (0.47) | TARBP2POLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5242268 | 0.83 | TARBP2 (0.59) | TARBP2POLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL17714992 | 0.83 | TARBP2 (0.59) | TARBP2POLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9514705 | 0.79 | TARBP2 (0.64) | TARBP2POLBKDM4EGSK3BMEN1 | |
| SCHEMBL17714991 | 0.79 | TARBP2 (0.55) | TARBP2POLBKDM4EALDH1A1CDK2 | |
| SCHEMBL16397007 | 0.78 | TARBP2 (0.47) | TARBP2POLBKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214299-A | Gamma-biphenyldicarboxylate intermediate, synthetic method thereof and gamma-biphenyldicarboxylate synthetic method | 重庆西南制药二厂有限责任公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113214299-A | Gamma-biphenyldicarboxylate intermediate, synthetic method thereof and gamma-biphenyldicarboxylate synthetic method | 重庆西南制药二厂有限责任公司 | 2021-08-06 | — | — | CN | disclosed |
| US-9328084-B2 | Nitrogen-containing biphenyl compounds, pharmaceutical compositions of same, preparation methods and anti-HIV-1 uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2016-05-03 | — | — | US | disclosed |
| US-9328084-B2 | Nitrogen-containing biphenyl compounds, pharmaceutical compositions of same, preparation methods and anti-HIV-1 uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2016-05-03 | — | — | US | disclosed |
| EP-0269754-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5032685-A | Hepatitis | TSUMURA JUNTENDO, INC. (JP) | 1991-07-16 | — | — | US | disclosed |
| US-4987240-A | PREFERENTIAL DEHALOGENATION OF CHEMICAL INTERMEDIATE | TSUMURA & CO. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4962211-A | MODERATING ACTION ON LIVER DISORDERS; CHEMICAL INTERMEDIATES; ACUTE AND CHRONIC HEPATITIS | TSUMURA & CO. (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4904694-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0269754-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-06-08 | — | — | EP | disclosed |