Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 5/20 | 0.73 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514705 | 0.92 | TARBP2 (0.64) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL9511802 | 0.91 | TARBP2 (0.63) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL17714984 | 0.88 | TARBP2 (0.77) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL17714981 | 0.87 | TARBP2 (0.60) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL5242268 | 0.85 | TARBP2 (0.59) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL17714992 | 0.85 | TARBP2 (0.59) | TARBP2GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL9514640 | 0.85 | TARBP2 (0.59) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL9512524 | 0.85 | TARBP2 (0.56) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL17714982 | 0.84 | TARBP2 (0.74) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL17714978 | 0.81 | TARBP2 (0.77) | TARBP2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269754-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-4987240-A | PREFERENTIAL DEHALOGENATION OF CHEMICAL INTERMEDIATE | TSUMURA & CO. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4962211-A | MODERATING ACTION ON LIVER DISORDERS; CHEMICAL INTERMEDIATES; ACUTE AND CHRONIC HEPATITIS | TSUMURA & CO. (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4904694-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0269754-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-06-08 | — | — | EP | disclosed |