Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 5/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATR | Q13535 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515570 | 0.92 | TARBP2 (0.73) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL9513890 | 0.88 | GSK3B (0.55) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL9330285 | 0.87 | POLB (0.51) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL9511802 | 0.84 | TARBP2 (0.63) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL11929030 | 0.82 | KDM4E (0.69) | KMT2AHTTPOLBKDM4EUSP2 | |
| SCHEMBL17714984 | 0.81 | TARBP2 (0.77) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL17714981 | 0.80 | TARBP2 (0.60) | TARBP2GSK3BMEN1KMT2AATR | |
| SCHEMBL12145714 | 0.79 | KDM4E (0.54) | TARBP2POLBKDM4EUSP2HSD17B10 | |
| SCHEMBL17714992 | 0.79 | TARBP2 (0.59) | TARBP2GSK3BMEN1KMT2AHTT | |
| SCHEMBL9514640 | 0.79 | TARBP2 (0.59) | TARBP2GSK3BMEN1KMT2AATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269754-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5032685-A | Hepatitis | TSUMURA JUNTENDO, INC. (JP) | 1991-07-16 | — | — | US | disclosed |
| US-4987240-A | PREFERENTIAL DEHALOGENATION OF CHEMICAL INTERMEDIATE | TSUMURA & CO. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4962211-A | MODERATING ACTION ON LIVER DISORDERS; CHEMICAL INTERMEDIATES; ACUTE AND CHRONIC HEPATITIS | TSUMURA & CO. (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4904694-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0269754-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-06-08 | — | — | EP | disclosed |