Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513456 | 0.88 | LMNA (0.45) | LMNACYP2C19HIF1A | |
| SCHEMBL9779853 | 0.88 | CNR2 (0.31) | LMNA | |
| SCHEMBL10436294 | 0.81 | LMNA (0.38) | LMNA | |
| SCHEMBL9516079 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL13873464 | 0.77 | LMNA (0.50) | LMNACYP2C19HIF1A | |
| SCHEMBL9514706 | 0.75 | LMNA (0.33) | LMNA | |
| SCHEMBL17123485 | 0.75 | LMNA (0.47) | LMNACYP2C19HIF1A | |
| SCHEMBL9356976 | 0.74 | LMNA (0.52) | LMNACYP2C19HIF1A | |
| SCHEMBL11286320 | 0.72 | LMNA (0.65) | LMNACYP2C19HIF1A | |
| SCHEMBL15711358 | 0.72 | LMNA (0.48) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357467-B1 | Non-ionic tri-iodobenzene compounds, and contrast agents containing same | GUERBET SA (FR) | 1993-12-08 | — | — | EP | disclosed |
| US-5043152-A | Radiography | GUERBET S.A. (FR) | 1991-08-27 | — | — | US | disclosed |
| EP-0357467-A1 | Non-ionic tri-iodobenzene compounds, and contrast agents containing same | GUERBET S.A. (FR) | 1990-03-07 | — | — | EP | disclosed |