SCHEMBL9516079

SCHEMBL9516079

CC(=O)OCC(CNC(=O)c1c(I)c(NC(=O)C2COC(C(C)C)OC2)c(I)c(NC(=O)C2COC(C(C)C)OC2)c1I)OC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ABCB1 P08183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4163484 0.87 LMNA (0.36) LMNAABCB1
SCHEMBL9513456 0.81 LMNA (0.45) LMNA
SCHEMBL17124727 0.80 LMNA (0.41) LMNAABCB1
SCHEMBL8379840 0.80 LMNA (0.39) LMNAABCB1
SCHEMBL8741512 0.80 SMN1; SMN2 (0.40) LMNA
SCHEMBL9514709 0.79 LMNA (0.42) LMNA
SCHEMBL8741511 0.79 LMNA (0.39) LMNAABCB1
SCHEMBL8593161 0.79
SCHEMBL3060308 0.78 LMNA (0.37) LMNAABCB1
SCHEMBL8377994 0.78 LMNA (0.38) LMNAABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357467-B1 Non-ionic tri-iodobenzene compounds, and contrast agents containing same GUERBET SA (FR) 1993-12-08 EP disclosed
US-5043152-A Radiography GUERBET S.A. (FR) 1991-08-27 US disclosed
EP-0357467-A1 Non-ionic tri-iodobenzene compounds, and contrast agents containing same GUERBET S.A. (FR) 1990-03-07 EP disclosed