Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402132 | 1.00 | FFAR1 (0.43) | FFAR1FFAR4PDCD1CD274PSMB5 | |
| SCHEMBL10013375 | 0.94 | PSMB5 (0.46) | PDCD1CD274PSMB5MMP1MMP8 | |
| SCHEMBL8935308 | 0.93 | PDCD1 (0.44) | PDCD1CD274PSMB5MMP1MMP8 | |
| SCHEMBL8935301 | 0.93 | PDCD1 (0.44) | PDCD1CD274PSMB5MMP1MMP8 | |
| SCHEMBL8935368 | 0.89 | FFAR1 (0.51) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL7397778 | 0.89 | FFAR1 (0.51) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL7441580 | 0.87 | FFAR1 (0.51) | FFAR1MMP8 | |
| SCHEMBL9129123 | 0.87 | FFAR1 (0.51) | FFAR1MMP8 | |
| SCHEMBL9133024 | 0.86 | FFAR1 (0.52) | FFAR1MMP8 | |
| SCHEMBL9514811 | 0.85 | ALDH1A1 (0.44) | PDCD1CD274PSMB5ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400495-B1 | N-phenylalkyl substituted alpha-amino carboxamide derivatives and process for their preparation. | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| EP-0400495-A1 | N-phenylalkyl substituted alfa-amino carboxamide derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-05 | — | — | EP | disclosed |