Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46384 | 0.78 | SRD5A1 (0.45) | CRBNMTNR1AHDAC1HDAC6ADRA2A | |
| SCHEMBL28618030 | 0.75 | GRIN2D (0.40) | CRBNMTNR1AHDAC1HDAC6ADRA2A | |
| SCHEMBL28708105 | 0.74 | CYP1A2 (0.48) | CRBNMTNR1AHDAC1HDAC6ADRA2A | |
| SCHEMBL13019291 | 0.74 | MTNR1A (0.38) | CRBNMTNR1AHDAC1HDAC6HDAC8 | |
| SCHEMBL28709051 | 0.74 | MTNR1A (0.38) | CRBNMTNR1AHDAC1HDAC6HDAC8 | |
| SCHEMBL21216167 | 0.70 | MTNR1A (0.38) | CRBNMTNR1AHDAC1HDAC6ADRA2A | |
| SCHEMBL29415783 | 0.69 | MTNR1A (0.42) | MTNR1AHDAC1HDAC6ADRA2AADRA2B | |
| SCHEMBL19224617 | 0.69 | MTNR1A (0.42) | MTNR1AHDAC1HDAC6ADRA2AADRA2B | |
| SCHEMBL28685861 | 0.68 | POLB (0.61) | HDAC1HDAC6HDAC8DRD2CHRM1 | |
| SCHEMBL8736481 | 0.67 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5017475-A | — | — | None | — | — | JP | disclosed |
| JP-H0517475-A | NEW 3,4-DIHYDRO-1,8-NAPHTHYRIDINE DERIVATIVE AND ANTI-BRONCHIAL ASTHMATIC CONTAINING THE SAME DERIVATIVE | SAPPORO BREWERIES LTD | 1993-01-26 | — | — | JP | disclosed |