Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145785 | 1.00 | NPC1 (0.48) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL9149957 | 1.00 | NPC1 (0.48) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL10526181 | 0.87 | NPC1 (0.50) | NPC1MAPTPTPN11LMNACYP1A2 | |
| SCHEMBL10526187 | 0.87 | NPC1 (0.50) | NPC1MAPTPTPN11LMNACYP1A2 | |
| SCHEMBL9510882 | 0.87 | PDE4A (0.44) | MAPTALDH1A1PTPN11THRATHRB | |
| SCHEMBL9150233 | 0.87 | PDE4A (0.44) | MAPTALDH1A1PTPN11THRATHRB | |
| SCHEMBL9149323 | 0.87 | PDE4A (0.54) | MAPTALDH1A1PTPN11LMNAPDE4A | |
| SCHEMBL9145185 | 0.85 | PTPN11 (0.48) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL9149296 | 0.85 | PTPN11 (0.48) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL9146241 | 0.85 | PTPN11 (0.48) | NPC1MAPTRAB9AALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |