Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 6/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150233 | 1.00 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL9149323 | 0.91 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9146142 | 0.90 | KIF11 (0.47) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL9514871 | 0.87 | NPC1 (0.48) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9149957 | 0.87 | NPC1 (0.48) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9145785 | 0.87 | NPC1 (0.48) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9149901 | 0.86 | MAPT (0.49) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL9647803 | 0.86 | PTPN11 (0.46) | PDE4APDE4BPDE4CPDE4DPTPN11 | |
| SCHEMBL6936499 | 0.85 | MGLL (0.43) | PDE4APDE4BPDE4CPDE4DRARB | |
| SCHEMBL9511961 | 0.85 | MGLL (0.43) | PDE4APDE4BPDE4CPDE4DRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272115-B1 | OPTICALLY ACTIVE LIQUID CRYSTALLINE BIPHENYL COMPOUND | Chisso Corporation (JP) | 1993-10-13 | — | — | EP | disclosed |
| US-4737313-A | OPITICALLY ACTIVE | CHISSO CORPORATION (JP) | 1988-04-12 | — | — | US | disclosed |