Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GART | P22102 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514877 | 1.00 | TYMS (0.55) | TYMSKDM4EHPGDGART | |
| SCHEMBL9385317 | 0.81 | TYMS (0.53) | TYMSKDM4EHPGDGART | |
| SCHEMBL9385323 | 0.81 | TYMS (0.53) | TYMSKDM4EHPGDGART | |
| SCHEMBL9515633 | 0.80 | GART (0.52) | TYMSKDM4EHPGDGART | |
| SCHEMBL9515649 | 0.80 | GART (0.52) | TYMSKDM4EHPGDGART | |
| SCHEMBL28614756 | 0.78 | TYMS (0.55) | TYMS | |
| SCHEMBL28614753 | 0.78 | TYMS (0.55) | TYMS | |
| SCHEMBL9817811 | 0.77 | L3MBTL1 (0.53) | TYMSKDM4EHPGD | |
| SCHEMBL9817805 | 0.77 | L3MBTL1 (0.53) | TYMSKDM4EHPGD | |
| SCHEMBL9515617 | 0.76 | KDM4E (0.46) | TYMSKDM4EHPGDGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284338-B1 | Anti-tumour agents | ICI PLC (GB) | 1993-12-22 | — | — | EP | disclosed |