Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 4/20 | 0.52 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.52 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 6/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932522 | 0.82 | IP6K1 (0.64) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL9514912 | 0.80 | CYP1A2 (0.46) | PARP1HRH4HRH3EPHX1 | |
| SCHEMBL8170598 | 0.78 | IP6K1 (0.71) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL9911097 | 0.78 | IP6K1 (0.66) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL27797161 | 0.77 | TNKS2 (0.48) | PARP1HRH4HRH3 | |
| SCHEMBL20334906 | 0.74 | IP6K1 (0.61) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL28100490 | 0.74 | IP6K1 (0.48) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL22980875 | 0.72 | IP6K1 (0.66) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL22042406 | 0.72 | IP6K1 (0.61) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL27947190 | 0.70 | IP6K1 (0.62) | IP6K1IP6K3IP6K2PARP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284338-B1 | Anti-tumour agents | ICI PLC (GB) | 1993-12-22 | — | — | EP | disclosed |