Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15732934 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4E | |
| SCHEMBL29978417 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4E | |
| SCHEMBL5481051 | 0.73 | ALDH1A1 (0.41) | ALDH1A1FGFR1RXFP1 | |
| SCHEMBL30112896 | 0.72 | CLK1 (0.43) | ALDH1A1KDM4ENUDT1LCKKDR | |
| SCHEMBL24506890 | 0.71 | ALDH1A1 (0.36) | ALDH1A1FGFR1NUDT1 | |
| SCHEMBL9798129 | 0.71 | PDXK (0.32) | — | |
| SCHEMBL30175533 | 0.70 | ADORA2A (0.45) | ALDH1A1FGFR1RXFP1 | |
| SCHEMBL2009621 | 0.70 | ADORA2A (0.45) | ALDH1A1FGFR1RXFP1 | |
| SCHEMBL25449339 | 0.70 | ALDH1A1 (0.35) | ALDH1A1FGFR1NUDT1 | |
| SCHEMBL25793171 | 0.70 | ALDH1A1 (0.35) | ALDH1A1FGFR1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290819-B1 | Pteridines suitable for the preparation of pharmaceutical compositions with antiamnesic activity | BIORESEARCH SPA (IT) | 1993-12-01 | — | — | EP | disclosed |
| US-5047405-A | Alzheimer*s disease | BIORESEARCH S.P.A. (IT) | 1991-09-10 | — | — | US | disclosed |
| EP-0290819-A2 | Pteridines suitable for the preparation of pharmaceutical compositions with antiamnesic activity | BIORESEARCH S.p.A. (IT) | 1988-11-17 | — | — | EP | disclosed |