SCHEMBL9515155

SCHEMBL9515155

CC1(CO)CC1c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 7/20 0.49
RCOR1 Q9UKL0 5/20 0.49
LIG1 P18858 1/20 0.45
PTGS2 P35354 1/20 0.39
MAPK1 P28482 2/20 0.38
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ELANE P08246 1/20 0.35
POLB P06746 1/20 0.34
ALOX12 P18054 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
DRD2 P14416 1/20 0.34
ABCC1 P33527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515156 1.00 KDM1A (0.49) KDM1ARCOR1LIG1PTGS2MAPK1
SCHEMBL1758191 0.83 ALDH1A1 (0.42) KDM1AALDH1A1MEN1KMT2AALOX12
SCHEMBL22995719 0.78 KDM1A (0.40) KDM1ARCOR1LIG1MAPK1ABCC1
SCHEMBL22995733 0.76 KDM1A (0.44) KDM1ARCOR1ALDH1A1MAPTATM
SCHEMBL4339855 0.76 KDM1A (0.53) KDM1ARCOR1LIG1MAPK1MEN1
SCHEMBL9974847 0.74 KDM1A (0.68) KDM1ARCOR1MAOAMAOB
SCHEMBL988382 0.73 PTGS2 (0.44) KDM1ARCOR1LIG1PTGS2DRD2
SCHEMBL9564707 0.73 KDM1A (0.41) KDM1ARCOR1LIG1MAPK1ALDH1A1
Bicarbonate SCHEMBL10971534 0.72 MAPK1 (0.50) KDM1ARCOR1LIG1PTGS2MAPK1
SCHEMBL321358 0.71 NR1I2 (0.49) KDM1ARCOR1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed