Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.74 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | PDE6D | O43924 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24517163 | 0.91 | THRB (0.81) | THRBFFAR1THRA | |
| SCHEMBL242424 | 0.90 | THRB (0.78) | THRBFFAR1PDE6DTHRAPPARG | |
| SCHEMBL19456765 | 0.88 | THRB (0.77) | THRBFFAR1PDE6DTHRAMAPT | |
| SCHEMBL2432065 | 0.86 | THRB (0.60) | THRBPDE6DPPARGPPARAMAPK1 | |
| SCHEMBL17791334 | 0.86 | THRB (0.79) | THRBFFAR1PDE6DTHRAPPARG | |
| SCHEMBL11031162 | 0.85 | THRB (1.00) | THRBTHRASLC6A3HPGD | |
| SCHEMBL28011377 | 0.85 | THRB (0.80) | THRBTHRAPPARGPPARA | |
| SCHEMBL13051048 | 0.84 | THRB (0.59) | THRBFFAR1PDE6DPPARGPPARA | |
| SCHEMBL10651481 | 0.84 | THRB (0.97) | THRBTHRASLC6A3 | |
| SCHEMBL6931228 | 0.84 | THRB (0.97) | THRBTHRASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1845911-B | Condensed ring compound and use thereof | ONO PHARMACEUTICAL CO | 2012-07-04 | — | — | CN | disclosed |
| CN-1845911-A | Condensed ring compound and use thereof | ONO PHARMACEUTICAL CO (JP) | 2006-10-11 | — | — | CN | disclosed |
| EP-0393547-B1 | Thermoplastic mouldings based on vinyl chloride | BASF AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| US-5166270-A | Blend with polymer of aromatic unsaturated ester; high heat distortion resistance | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0393547-A1 | Thermoplastic mouldings based on vinyl chloride | BASF Aktiengesellschaft (DE) | 1990-10-24 | — | — | EP | disclosed |