SCHEMBL2432065

SCHEMBL2432065

C=CC(=O)Oc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.60
PDE6D O43924 1/20 0.50
PPARG P37231 3/20 0.49
PPARA Q07869 3/20 0.49
SRD5A2 P31213 1/20 0.49
LTA4H P09960 4/20 0.48
ELANE P08246 1/20 0.47
LMNA P02545 2/20 0.46
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
MAPK1 P28482 1/20 0.44
CASP3 P42574 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LIPE Q05469 1/20 0.44
CALM1 P0DP23 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580708 0.93 THRB (0.68) THRBPDE6DPPARGPPARASRD5A2
SCHEMBL13084272 0.89 THRB (0.54) THRBPDE6DPPARGPPARASRD5A2
SCHEMBL13777578 0.88 THRB (0.55) THRBPDE6DPPARGPPARASRD5A2
SCHEMBL9515263 0.86 THRB (0.74) THRBPDE6DPPARGPPARALTA4H
SCHEMBL9406873 0.86 THRB (0.60) THRBPDE6DSRD5A2ELANE
SCHEMBL10891821 0.85 THRB (0.47) THRBPDE6DSRD5A2
SCHEMBL13051034 0.85 THRB (0.55) THRBPDE6DL3MBTL1
SCHEMBL28010934 0.83 NR4A1 (0.60) THRBPPARGPPARASRD5A2LMNA
Hydrogen Peroxide SCHEMBL28479331 0.82 THRB (0.58) THRBPDE6DMAPK1L3MBTL1
SCHEMBL28916 0.82 THRB (0.58) THRBPDE6DMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060261318-A1 Light control film SUMITOMO CHEMICAL COMPANY, LIMITED 2006-11-23 US claimed
US-20230348763-A1 UV-CURABLE SEMI-STRUCTURAL ADHESIVE, AND UV-CURABLE SEMI-STRUCTURAL ADHESIVE TAPE 3M INNOVATIVE PROPERTIES COMPANY 2023-11-02 US disclosed
US-20130046087-A1 Substituted Cyclodextrin Derivatives Useful As Intermediates For Producing Biologically Active Materials ARCARIOS BV (NL) 2013-02-21 US disclosed
EP-2550299-A2 Substituted cyclodextrin derivatives and process for their preparation Arcarios B.V. (NL) 2013-01-30 EP disclosed
WO-2011117317-A2 SUBSTITUTED CYCLODEXTRIN DERIVATIVES USEFUL AS INTERMEDIATES FOR PRODUCING BIOLOGICALLY ACTIVE MATERIALS ARCARIOS BV (NL) 2011-09-29 WO disclosed
US-20090247661-A1 POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX CORONIS GMBH (DE) 2009-10-01 US disclosed
US-20090247661-A1 POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX CORONIS GMBH (DE) 2009-10-01 US disclosed
US-20060261318-A1 Light control film SUMITOMO CHEMICAL COMPANY, LIMITED 2006-11-23 US disclosed
EP-0145263-B1 LIVING POLYMERS AND PROCESS FOR THEIR PREPARATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-17 EP disclosed
US-4957973-A GROUP TRANSFER POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-18 US disclosed
US-4581428-A Process for preparing \"living\" polymers using tetracoordinate organosilicon, organotin or organogermanium polymerization initiator with bifluoride ion source co-catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-08 US disclosed
EP-0145263-A1 Living polymers and process for their preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-06-19 EP disclosed
US-4524196-A Process for preparing \"living\" polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-06-18 US disclosed
US-4508880-A ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-02 US disclosed
US-4269933-A PHOTOLITHOGRAPHY; POSITIVE AND NEGATIVE IMAGES; POLYMERIZATION OF A UNSATURATED POLYESTER USING A PHOTOSENSITIVE FREE RADICAL SYSTEM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-26 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4198242-A Photopolymerizable composition containing an o-nitroaromatic compound as photoinhibitor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-15 US disclosed
US-4168981-A Bis(substituted amino)sulfides as reversible inhibitor sources for photopolymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-25 US disclosed
US-4168982-A Photopolymerizable compositions containing nitroso dimers to selectively inhibit thermal polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-25 US disclosed
US-4029505-A PHOTOPOLYMERIZABLE LAYER OF UNSATURATED COMPOUND, DINITROSO COMPOUND, AND FREE-RADICAL GENERATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247661-A1 POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX RPIA, PDE6D, PDE6A THRB 4562/4885PDE6D 2/4885PPARG 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.